EEG Testing May Predict Clozapine Response in Treatment-Resistant Schizophrenia

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Electroencephalography (EEG) testing may be able to predict response to clozapine in patients with treatment-resistant schizophrenia a new pilot study suggests.

In fact, the response prediction accuracy rate was over 85% during both the first part of the study, where a computer algorithm was “trained” using brainwave patterns from a group of clozapine-naive patients, and during the second part, where additional patients were tested, report researchers from McMaster University in Hamilton, Ontario.

“We found that certain brainwave patterns, particularly in the back half of the brain on the left side, seem to be predictive of whether a person would respond to clozapine or not,” study coauthor Gary Hasey, MD, associate professor in the Department of Psychiatry and Behavioral Neurosciences at McMaster and director of the Transcranial Magnetic Stimulation Laboratory and the Mood Disorders Program at St. Joseph Hospital, told Medscape Medical News.

Reported by Deborah Brauser
Medscape
http://www.medscape.com/viewarticle/727098

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