Both low and high levels of neonatal vitamin D may increase risk for the eventual development of schizophrenia, according to a population-based case-control study of 848 patients in Denmark.
“Vitamin D during early life is associated with altered brain growth [due to] good evidence from animal studies and now this new link from the Danish study,” John J. McGrath, MD, PhD, professor at the Queensland Brain Institute at the University of Queensland in St. Lucia, Australia, told Medscape Medical News.
Therefore, “we need to think about prenatal vitamin D supplements for women at risk of low vitamin D,” said Dr. McGrath.
He was surprised, though, about the link with high levels. “The results were curious; we found what we predicted [that lower neonatal vitamin D level was associated with higher risk for schizophrenia], but also we got a hint that there might be a subgroup of babies who are mildly resistant to vitamin D,” he said. For this area, “more work needs to be done.
Reported by Deborah Brauser
Submitted by Anna