A brain imaging technique may help predict whether people with major depression will respond best to treatment with psychotherapy or a commonly prescribed drug. The approach might eventually be used as a tool to identify treatments that are most likely to succeed.
People with major depressive disorder, or major depression, have feelings of sadness, loss, anger or frustration that interfere with daily life for weeks or longer. Symptoms can also include memory loss and trouble focusing.
Major depression is most commonly treated with medication, psychotherapy or a combination. Unfortunately, less than 40% of patients typically respond well to initial treatment. They may need to try several treatments over many weeks or months before finally getting symptom relief.
–National Institutes of Health (NIH)