Experimental Tool Uses Light To Tweak The Living Brain

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When President Obama announced his BRAIN Initiative in April, he promised to give scientists “the tools they need to get a dynamic picture of the brain in action.”

An early version of one of those tools already exists, scientists say. It’s a relatively new set of techniques called optogenetics that allows researchers to control the activity of brain cells using light.

“This is fantastic,” says Elizabeth Hillman, a biomedical engineer at Columbia University. “We can turn things on, turn things off, read stuff out.” In short, she says, it provides a way to observe and control what brain circuits are doing in real time in a living brain.

Eventually, optogenetics could not only help explain diseases like epilepsy and depression, but offer a way to treat them. But the technique needs some refinement before it can be used in people or in remote parts of the brain, Hillman says.

by Jon Hamilton, NPR

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